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A Hip1R–cortactin complex negatively regulates actin assembly associated with endocytosis

Actin polymerization plays a critical role in clathrin-mediated endocytosis in many cell types, but how polymerization is regulated is not known. Hip1R may negatively regulate actin assembly during endocytosis because its depletion increases actin assembly at endocytic sites. Here, we show that the...

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Detalhes bibliográficos
Main Authors: Le Clainche, Christophe, Pauly, Barbara S, Zhang, Claire X, Engqvist-Goldstein, Åsa E Y, Cunningham, Kimberley, Drubin, David G
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2007
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1817625/
https://ncbi.nlm.nih.gov/pubmed/17318189
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.emboj.7601576
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