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New plasmid-mediated aminoglycoside adenylyltransferase of broad substrate range that adenylylates amikacin.

The same aminoglycoside 2"-adenylyltransferase was isolated from four gram-negative species which were among a random group of gentamicin-resistant isolates from the same hospital. The enzyme was partially purified from a crude extract which also contained a second modifying enzyme identified as APH...

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Bibliographic Details
Published in:Antimicrob Agents Chemother
Main Authors: Coombe, R G, George, A M
Format: Artigo
Language:Inglês
Published: American Society for Microbiology (ASM) 1981
Subjects:
Online Access:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC181636/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/6269486/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/aac.20.1.75
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