Plasma disappearance, urine excretion, and tissue distribution of ribavirin in rats and rhesus monkeys.

Ribavirin has been shown to have broad-spectrum antiviral. To study its tissue distribution and disappearance rate, a single dose of 10 mg/kg which contained 10 microCi of [14C]ribavirin was injected intravenously into rhesus monkeys and intramuscularly into monkeys and rats. Except for peak plasma...

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Veröffentlicht in:	Antimicrob Agents Chemother
Hauptverfasser:	Ferrara, E A, Oishi, J S, Wannemacher, R W, Stephen, E L
Format:	Artigo
Sprache:	Inglês
Veröffentlicht:	American Society for Microbiology (ASM) 1981
Schlagworte:	Research Article
Online-Zugang:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC181605/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/7271273/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/aac.19.6.1042
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