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Protein kinase A activates protein phosphatase 2A by phosphorylation of the B56δ subunit

Our previous studies of DARPP-32 in striatal slices have shown that activation of D1 receptors leads to cAMP-dependent dephosphorylation of Thr-75, the Cdk5 site in DARPP-32. In the current study, we have elucidated a mechanism whereby protein phosphatase 2A (PP2A) is activated by a cAMP/PKA-depende...

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Hlavní autoři: Ahn, Jung-Hyuck, McAvoy, Thomas, Rakhilin, Sergey V., Nishi, Akinori, Greengard, Paul, Nairn, Angus C.
Médium: Artigo
Jazyk:Inglês
Vydáno: National Academy of Sciences 2007
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On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC1815292/
https://ncbi.nlm.nih.gov/pubmed/17301223
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0611532104
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