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Dido disruption leads to centrosome amplification and mitotic checkpoint defects compromising chromosome stability

Numerical and/or structural centrosome abnormalities have been correlated with most solid tumors and hematological malignancies. Tumorigenesis also is linked to defects in the mitotic or spindle assembly checkpoint, a key control mechanism that ensures accurate segregation of chromosomes during mito...

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Main Authors: Trachana, Varvara, van Wely, Karel H. M., Guerrero, Astrid Alonso, Fütterer, Agnes, Martínez-A, Carlos
Formato: Artigo
Idioma:Inglês
Publicado: National Academy of Sciences 2007
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC1815243/
https://ncbi.nlm.nih.gov/pubmed/17299043
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0611132104
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