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Dido disruption leads to centrosome amplification and mitotic checkpoint defects compromising chromosome stability
Numerical and/or structural centrosome abnormalities have been correlated with most solid tumors and hematological malignancies. Tumorigenesis also is linked to defects in the mitotic or spindle assembly checkpoint, a key control mechanism that ensures accurate segregation of chromosomes during mito...
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| Main Authors: | , , , , |
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| 格式: | Artigo |
| 語言: | Inglês |
| 出版: |
National Academy of Sciences
2007
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| 主題: | |
| 在線閱讀: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1815243/ https://ncbi.nlm.nih.gov/pubmed/17299043 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0611132104 |
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