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Ultrafast dynamics of protein collapse from single-molecule photon statistics

We use the statistics of photon emission from single molecules to probe the ultrafast dynamics of an unfolded protein via Förster resonance energy transfer. Global reconfiguration of the chain occurs on a time scale of ≈50 ns and slows down concomitant with chain collapse under folding conditions. T...

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Autori principali: Nettels, Daniel, Gopich, Irina V., Hoffmann, Armin, Schuler, Benjamin
Natura: Artigo
Lingua:Inglês
Pubblicazione: National Academy of Sciences 2007
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC1815237/
https://ncbi.nlm.nih.gov/pubmed/17301233
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0611093104
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