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Liquid chromatographic assay for metronidazole and tinidazole: pharmacokinetic and metabolic studies in human subjects.

We developed methods for measuring metronidazole, its two major metabolites, and tinidazole in serum and urine. After treatment of each sample with an equal volume of 5% perchloric acid, the drugs were separated by reverse-phase high-pressure liquid chromatography (retention times, 6 to 18 min). Qua...

תיאור מלא

שמור ב:
מידע ביבליוגרפי
הוצא לאור ב:Antimicrob Agents Chemother
Principais autores: Nilsson-Ehle, I, Ursing, B, Nilsson-Ehle, P
פורמט: Artigo
שפה:Inglês
יצא לאור: American Society for Microbiology (ASM) 1981
נושאים:
גישה מקוונת:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC181517/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/7294765/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/aac.19.5.754
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