Liquid chromatographic assay for metronidazole and tinidazole: pharmacokinetic and metabolic studies in human subjects.

We developed methods for measuring metronidazole, its two major metabolites, and tinidazole in serum and urine. After treatment of each sample with an equal volume of 5% perchloric acid, the drugs were separated by reverse-phase high-pressure liquid chromatography (retention times, 6 to 18 min). Qua...

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Pubblicato in:	Antimicrob Agents Chemother
Autori principali:	Nilsson-Ehle, I, Ursing, B, Nilsson-Ehle, P
Natura:	Artigo
Lingua:	Inglês
Pubblicazione:	American Society for Microbiology (ASM) 1981
Soggetti:	Research Article
Accesso online:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC181517/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/7294765/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/aac.19.5.754
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