Signal-dependent activation of the MEF2 transcription factor by dissociation from histone deacetylases

Myocyte enhancer factor-2 (MEF2) transcription factors control muscle-specific and growth factor-inducible genes. We show that hypertrophic growth of cardiomyocytes in response to phenylephrine and serum is accompanied by activation of MEF2 through a posttranslational mechanism mediated by calcium,...

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Veröffentlicht in:	Proc Natl Acad Sci U S A
Hauptverfasser:	Lu, Jianrong, McKinsey, Timothy A., Nicol, Rebekka L., Olson, Eric N.
Format:	Artigo
Sprache:	Inglês
Veröffentlicht:	National Academy of Sciences 2000
Schlagworte:	Biological Sciences
Online-Zugang:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC18151/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/10737771/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.080064097
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