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Signal-dependent activation of the MEF2 transcription factor by dissociation from histone deacetylases

Myocyte enhancer factor-2 (MEF2) transcription factors control muscle-specific and growth factor-inducible genes. We show that hypertrophic growth of cardiomyocytes in response to phenylephrine and serum is accompanied by activation of MEF2 through a posttranslational mechanism mediated by calcium,...

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Hlavní autoři: Lu, Jianrong, McKinsey, Timothy A., Nicol, Rebekka L., Olson, Eric N.
Médium: Artigo
Jazyk:Inglês
Vydáno: The National Academy of Sciences 2000
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC18151/
https://ncbi.nlm.nih.gov/pubmed/10737771
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