Pharmacology of cefotaxime and its desacetyl metabolite in renal and hepatic disease.

The pharmacology of cefotaxime and the metabolite desacetyl cefotaxime was studied in 40 patients with various degrees of renal and hepatic failure who received 0.5 or 1 g of cefotaxime intravenously. Patients with severe renal impairment (creatinine clearance, 3 to 10 ml/min) had a cefotaxime serum...

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Εκδόθηκε σε:	Antimicrob Agents Chemother
Κύριοι συγγραφείς:	Wise, R, Wright, N, Wills, P J
Μορφή:	Artigo
Γλώσσα:	Inglês
Έκδοση:	American Society for Microbiology (ASM) 1981
Θέματα:	Research Article
Διαθέσιμο Online:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC181470/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/6264849/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/aac.19.4.526
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