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Pharmacology of cefotaxime and its desacetyl metabolite in renal and hepatic disease.

The pharmacology of cefotaxime and the metabolite desacetyl cefotaxime was studied in 40 patients with various degrees of renal and hepatic failure who received 0.5 or 1 g of cefotaxime intravenously. Patients with severe renal impairment (creatinine clearance, 3 to 10 ml/min) had a cefotaxime serum...

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Detalhes bibliográficos
Publicado no:Antimicrob Agents Chemother
Principais autores: Wise, R, Wright, N, Wills, P J
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology (ASM) 1981
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC181470/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/6264849/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/aac.19.4.526
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