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Effects of vancomycin on renal function in rats.

To assess the effects of vancomycin on the kidney, we gave rats doses of 10, 50, 100, 200, and 400 mg/kg per day. Creatinine clearance and urine protein excretion did not differ significantly from the control values. Urine osmolality was unchanged. Mild histological changes occurred in rats given th...

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Detalhes bibliográficos
Publicado no:Antimicrob Agents Chemother
Principais autores: Aronoff, G R, Sloan, R S, Dinwiddie, C B, Glant, M D, Fineberg, N S, Luft, F C
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology (ASM) 1981
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC181415/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/7347562/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/aac.19.2.306
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