Effects of vancomycin on renal function in rats.

To assess the effects of vancomycin on the kidney, we gave rats doses of 10, 50, 100, 200, and 400 mg/kg per day. Creatinine clearance and urine protein excretion did not differ significantly from the control values. Urine osmolality was unchanged. Mild histological changes occurred in rats given th...

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Publicado en:	Antimicrob Agents Chemother
Principais autores:	Aronoff, G R, Sloan, R S, Dinwiddie, C B, Glant, M D, Fineberg, N S, Luft, F C
Formato:	Artigo
Idioma:	Inglês
Publicado:	American Society for Microbiology (ASM) 1981
Assuntos:	Research Article
Acceso en liña:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC181415/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/7347562/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/aac.19.2.306
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