Ribosomal binding region for the antibiotic tiamulin: stoichiometry, subunit location, and affinity for various analogs.
Equilibrium dialysis experiments with a highly purified preparation of labeled tiamulin, a semisynthetic derivative of the antibiotic pleuromutilin, and Escherichia coli ribosomes allowed the determination of two binding sites for the drug. The binding reaction showed a cooperative effect. Of the tw...
Guardat en:
| Publicat a: | Antimicrob Agents Chemother |
|---|---|
| Autors principals: | , |
| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
American Society for Microbiology (ASM)
1981
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC181405/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/6751216/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/aac.19.2.260 |
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