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Txk, a member of the non-receptor tyrosine kinase of the Tec family, forms a complex with poly(ADP-ribose) polymerase 1 and elongation factor 1α and regulates interferon-γ gene transcription in Th1 cells

We have found previously that Txk, a member of the Tec family tyrosine kinases, is involved importantly in T helper 1 (Th1) cytokine production. However, how Txk regulates interferon (IFN)-γ gene transcription in human T lymphocytes was not fully elucidated. In this study, we identified poly(ADP-rib...

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Autori principali: Maruyama, T, Nara, K, Yoshikawa, H, Suzuki, N
Natura: Artigo
Lingua:Inglês
Pubblicazione: Blackwell Science Inc 2007
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC1810450/
https://ncbi.nlm.nih.gov/pubmed/17177976
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1365-2249.2006.03249.x
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