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Excessive expression of Txk, a member of the Tec family of tyrosine kinases, contributes to excessive Th1 cytokine production by T lymphocytes in patients with Behcet's disease

Excessive Th1 cell function is importantly involved in the pathogenesis of Behcet's disease (BD). We previously found that Txk, a member of the Tec family of tyrosine kinases, acts as a Th1 cell specific transcription factor. To investigate immune aberration in the pathogenesis of BD, we studie...

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Autors principals: Nagafuchi, H, Takeno, M, Yoshikawa, H, Kurokawa, M S, Nara, K, Takada, E, Masuda, C, Mizoguchi, M, Suzuki, N
Format: Artigo
Idioma:Inglês
Publicat: Blackwell Science Inc 2005
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC1809281/
https://ncbi.nlm.nih.gov/pubmed/15654836
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1365-2249.2004.02688.x
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