Severe fibrosis in hepatitis C virus-infected patients is associated with increased activity of the mannan-binding lectin (MBL)/MBL-associated serine protease 1 (MASP-1) complex

Mannan-binding lectin (MBL) binds microorganisms via interactions with glycans on the target surface. Bound MBL subsequently activates MBL-associated serine protease proenzymes (MASPs). A role for MBL in hepatitis C virus (HCV) infection had been indicated by previous studies examining MBL levels an...

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Bibliografiset tiedot
Päätekijät: Brown, K S, Keogh, M J, Tagiuri, N, Grainge, M J, Presanis, J S, Ryder, S D, Irving, W L, Ball, J K, Sim, R B, Hickling, T P
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: Blackwell Science Inc 2007
Aiheet:
Clinical Studies
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC1810446/
https://ncbi.nlm.nih.gov/pubmed/17177967
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1365-2249.2006.03264.x
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