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MLN51 Stimulates the RNA-Helicase Activity of eIF4AIII

The core of the exon-junction complex consists of Y14, Magoh, MLN51 and eIF4AIII, a DEAD-box RNA helicase. MLN51 stimulates the ATPase activity of eIF4AIII, whilst the Y14-Magoh complex inhibits it. We show that the MLN51-dependent stimulation increases both the affinity of eIF4AIII for ATP and the...

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Detalhes bibliográficos
Main Authors: Noble, Christian G., Song, Haiwei
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2007
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1810427/
https://ncbi.nlm.nih.gov/pubmed/17375189
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0000303
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