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The activity of the immunoregulatory enzyme indoleamine 2,3-dioxygenase is decreased in smokers
Indoleamine 2,3-dioxygenase (IDO), an enzyme involved in the degradation of the essential amino acid tryptophan (trp) to its main metabolite kynurenine (kyn), suppresses T cell activity. Smoking has marked immunomodulatory effects, above all immunosuppressive, causing a reduction in the levels of im...
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| Main Authors: | , , , , , |
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| 格式: | Artigo |
| 語言: | Inglês |
| 出版: |
Blackwell Science Inc
2006
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| 主題: | |
| 在線閱讀: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1809700/ https://ncbi.nlm.nih.gov/pubmed/16907915 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1365-2249.2006.03166.x |
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