The activity of the immunoregulatory enzyme indoleamine 2,3-dioxygenase is decreased in smokers

Indoleamine 2,3-dioxygenase (IDO), an enzyme involved in the degradation of the essential amino acid tryptophan (trp) to its main metabolite kynurenine (kyn), suppresses T cell activity. Smoking has marked immunomodulatory effects, above all immunosuppressive, causing a reduction in the levels of im...

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Main Authors: Pertovaara, M, Heliövaara, M, Raitala, A, Oja, S S, Knekt, P, Hurme, M
Format: Artigo
Jezik:Inglês
Izdano: Blackwell Science Inc 2006
Teme:
Clinical Studies
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC1809700/
https://ncbi.nlm.nih.gov/pubmed/16907915
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1365-2249.2006.03166.x
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