Arthritogenicity of collagen type II is increased by chlorination

SUMMARY: During inflammation, activated neutrophils, monocytes and macrophages produce and release myeloperoxidase (MPO). MPO converts hydrogen peroxide to hypochlorous acid, a highly reactive and oxidizing agent. Proteins subjected to hypochlorous acid become chlorinated. We analysed how chlorinati...

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Autores principales: Westman, E, Lundberg, K, Erlandsson Harris, H
Formato: Artigo
Lenguaje:Inglês
Publicado: Blackwell Science Inc 2006
Materias:
Animal Studies
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC1809685/
https://ncbi.nlm.nih.gov/pubmed/16879255
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1365-2249.2006.03129.x
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