Potentiation of Tumor Necrosis Factor-Induced NF-κB Activation by Deacetylase Inhibitors Is Associated with a Delayed Cytoplasmic Reappearance of IκBα

Previous studies have implicated acetylases and deacetylases in regulating the transcriptional activity of NF-κB. Here, we show that inhibitors of deacetylases such as trichostatin A (TSA) and sodium butyrate (NaBut) potentiated TNF-induced expression of several natural NF-κB-driven promoters. This...

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Detalhes bibliográficos
Main Authors: Adam, Emmanuelle, Quivy, Vincent, Bex, Françoise, Chariot, Alain, Collette, Yves, Vanhulle, Caroline, Schoonbroodt, Sonia, Goffin, Véronique, Nguyên, Thi Liên-Anh, Gloire, Geoffrey, Carrard, Géraldine, Friguet, Bertrand, de Launoit, Yvan, Burny, Arsène, Bours, Vincent, Piette, Jacques, Lint, Carine Van
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2003
Assuntos:
Cell Growth and Development
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC180966/
https://ncbi.nlm.nih.gov/pubmed/12917341
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.23.17.6200-6209.2003
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