Potentiation of Tumor Necrosis Factor-Induced NF-κB Activation by Deacetylase Inhibitors Is Associated with a Delayed Cytoplasmic Reappearance of IκBα

Previous studies have implicated acetylases and deacetylases in regulating the transcriptional activity of NF-κB. Here, we show that inhibitors of deacetylases such as trichostatin A (TSA) and sodium butyrate (NaBut) potentiated TNF-induced expression of several natural NF-κB-driven promoters. This...

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Detalhes bibliográficos

Publicado no:	Mol Cell Biol
Principais autores:	Adam, Emmanuelle, Quivy, Vincent, Bex, Françoise, Chariot, Alain, Collette, Yves, Vanhulle, Caroline, Schoonbroodt, Sonia, Goffin, Véronique, Nguyên, Thi Liên-Anh, Gloire, Geoffrey, Carrard, Géraldine, Friguet, Bertrand, de Launoit, Yvan, Burny, Arsène, Bours, Vincent, Piette, Jacques, Lint, Carine Van
Formato:	Artigo
Idioma:	Inglês
Publicado em:	Taylor & Francis 2003
Assuntos:	Cell Growth and Development
Acesso em linha:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC180966/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/12917341/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/MCB.23.17.6200-6209.2003
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