Glatiramer acetate reduces lymphocyte proliferation and enhances IL-5 and IL-13 production through modulation of monocyte-derived dendritic cells in multiple sclerosis

Dendritic cells (DC), as the most effective antigen presenting cells, are protagonists of the complex immune network involved in multiple sclerosis (MS) lesion formation. Glatiramer acetate (GA), a synthetic random copolymer, is thought to exert its therapeutical effect in MS by favouring both Th2 c...

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Main Authors: Sanna, A, Fois, M L, Arru, G, Huang, Y-M, Link, H, Pugliatti, M, Rosati, G, Sotgiu, S
Formato: Artigo
Idioma:Inglês
Publicado: Blackwell Science Inc 2006
Assuntos:
Clinical Studies
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC1809576/
https://ncbi.nlm.nih.gov/pubmed/16412061
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1365-2249.2006.02997.x
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