Glatiramer acetate reduces lymphocyte proliferation and enhances IL-5 and IL-13 production through modulation of monocyte-derived dendritic cells in multiple sclerosis

Dendritic cells (DC), as the most effective antigen presenting cells, are protagonists of the complex immune network involved in multiple sclerosis (MS) lesion formation. Glatiramer acetate (GA), a synthetic random copolymer, is thought to exert its therapeutical effect in MS by favouring both Th2 c...

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Enregistré dans:
Détails bibliographiques
Auteurs principaux: Sanna, A, Fois, M L, Arru, G, Huang, Y-M, Link, H, Pugliatti, M, Rosati, G, Sotgiu, S
Format: Artigo
Langue:Inglês
Publié: Blackwell Science Inc 2006
Sujets:
Clinical Studies
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC1809576/
https://ncbi.nlm.nih.gov/pubmed/16412061
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1365-2249.2006.02997.x
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