Differential regulation of interleukin-12 and tumour necrosis factor-α by phosphatidylinositol 3-kinase and ERK 1/2 pathways during Mycobacterium tuberculosis infection

Interleukin (IL)-12 and tumour necrosis factor (TNF)-α are both thought to be critical factors in the defence against mycobacteria but are known to play different roles. In this study, we investigated the regulatory pathways for IL-12 and TNF-α expression in human monocyte-derived macrophages (MDMs)...

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Bibliografske podrobnosti
Main Authors: Yang, C-S, Lee, J-S, Jung, S-B, Oh, J-H, Song, C-H, Kim, H-J, Park, J-K, Paik, T-H, Jo, E-K
Format: Artigo
Jezik:Inglês
Izdano: Blackwell Science Inc 2006
Teme:
Clinical Studies
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC1809561/
https://ncbi.nlm.nih.gov/pubmed/16367946
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1365-2249.2005.02966.x
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