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Inhibition of classical complement activation attenuates liver ischaemia and reperfusion injury in a rat model

Activation of the complement system contributes to the pathogenesis of ischaemia/reperfusion (I/R) injury. We evaluated inhibition of the classical pathway of complement using C1-inhibitor (C1-inh) in a model of 70% partial liver I/R injury in male Wistar rats (n = 35). C1-inh was administered at 10...

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Detalhes bibliográficos
Main Authors: Heijnen, B H M, Straatsburg, I H, Padilla, N D, Van Mierlo, G J, Hack, C E, Van Gulik, T M
Formato: Artigo
Idioma:Inglês
Publicado em: Blackwell Science Inc 2006
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1809558/
https://ncbi.nlm.nih.gov/pubmed/16367929
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1365-2249.2005.02958.x
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