Short-term treatment with anti-CD44v7 antibody, but not CD44v4, restores the gut mucosa in established chronic dextran sulphate sodium (DSS)-induced colitis in mice

Increased expression of CD44 variant isoforms have been shown on the inflammatory infiltrates in human and mouse colitis and blockade or deletion of CD44 isoforms inhibit experimental colitis. The objective of this study was to find out if short-term treatment of CD44 antibodies specific to CD44v7,...

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Detalhes bibliográficos
Main Authors: Farkas, S, Hornung, M, Sattler, C, Anthuber, M, Gunthert, U, Herfarth, H, Schlitt, HJ, Geissler, EK, Wittig, BM
Formato: Artigo
Idioma:Inglês
Publicado em: Blackwell Science Inc 2005
Assuntos:
Animal Studies
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1809521/
https://ncbi.nlm.nih.gov/pubmed/16232212
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1365-2249.2005.02911.x
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