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Functional profile of human influenza virus-specific cytotoxic T lymphocyte activity is influenced by interleukin-2 concentration and epitope specificity

The ability of influenza A virus-specific cytotoxic T lymphocytes (CTL) to degranulate and produce cytokines upon antigenic restimulation was studied in four HLA-A*0101 and HLA-A*0201 positive subjects. Peripheral blood mononuclear cells of these subjects were stimulated with influenza A virus in th...

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Autors principals: Boon, ACM, de Mutsert, G, Fouchier, RAM, Osterhaus, ADME, Rimmelzwaan, GF
Format: Artigo
Idioma:Inglês
Publicat: Blackwell Science Inc 2005
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC1809493/
https://ncbi.nlm.nih.gov/pubmed/16178855
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1365-2249.2005.02880.x
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