The Hypervariable Immunodominant NP(418-426) Epitope from the Influenza A Virus Nucleoprotein Is Recognized by Cytotoxic T Lymphocytes with High Functional Avidity

Recently it was shown that influenza A viruses can accumulate mutations in epitopes associated with escape from recognition by human virus-specific cytotoxic T lymphocytes (CTL). It is unclear what drives diversification of CTL epitopes and why certain epitopes are variable and others remain conserv...

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מידע ביבליוגרפי
Main Authors: Boon, Adrianus C. M., de Mutsert, Gerrie, Fouchier, Ron A. M., Osterhaus, Albert D. M. E., Rimmelzwaan, Guus F.
פורמט: Artigo
שפה:Inglês
יצא לאור: American Society for Microbiology 2006
נושאים:
Pathogenesis and Immunity
גישה מקוונת:https://ncbi.nlm.nih.gov/pmc/articles/PMC1472604/
https://ncbi.nlm.nih.gov/pubmed/16731941
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.00009-06
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