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High levels of glucocorticoid receptors in patients with active Crohn's disease may predict steroid resistance

Up to 20% of Crohn's disease (CD) patients respond poorly to glucocorticoids (GC). A product of an alternative splicing of the glucocorticoid receptor (GR) premRNA, GRβ, may play a role as a dominant inhibitor of the glucocorticoid response. Increasing evidence suggests that inflammatory cytoki...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Egile Nagusiak: Towers, R, Naftali, T, Gabay, G, Carlebach, M, Klein, A, Novis, B
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: Blackwell Science Inc 2005
Gaiak:
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC1809436/
https://ncbi.nlm.nih.gov/pubmed/15996200
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1365-2249.2005.02846.x
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