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High levels of glucocorticoid receptors in patients with active Crohn's disease may predict steroid resistance
Up to 20% of Crohn's disease (CD) patients respond poorly to glucocorticoids (GC). A product of an alternative splicing of the glucocorticoid receptor (GR) premRNA, GRβ, may play a role as a dominant inhibitor of the glucocorticoid response. Increasing evidence suggests that inflammatory cytoki...
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| Hauptverfasser: | , , , , , |
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| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
Blackwell Science Inc
2005
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1809436/ https://ncbi.nlm.nih.gov/pubmed/15996200 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1365-2249.2005.02846.x |
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