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Deficiency of the mannan-binding lectin pathway of complement and poor outcome in cystic fibrosis: bacterial colonization may be decisive for a relationship

In cystic fibrosis (CF) prognosis concerning lung damage development is highly variable and difficult to predict. Mannan-binding lectin (MBL) deficiency has been reported to be associated with poor outcome in CF lung disease. MBL is a recognition molecule of the MBL pathway of the complement system...

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Autors principals: Carlsson, M, Sjöholm, A G, Eriksson, L, Thiel, S, Jensenius, J C, Segelmark, M, Truedsson, L
Format: Artigo
Idioma:Inglês
Publicat: Blackwell Science Inc 2005
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC1809291/
https://ncbi.nlm.nih.gov/pubmed/15654829
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1365-2249.2004.02690.x
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