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Autoantibodies to a collagen-specific molecular chaperone, heat-shock protein 47, in systemic sclerosis

Heat-shock proteins are highly conserved and immunogenic proteins, which may be involved in the initiation and perpetuation of autoimmune diseases. Heat-shock protein 47 (HSP47) is expressed by collagen-secreting cells such as fibroblasts and serves as a collagen-specific molecular chaperone that pl...

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Main Authors: FUJIMOTO, M, HAMAGUCHI, Y, YAZAWA, N, KOMURA, K, TAKEHARA, K, SATO, S
格式: Artigo
語言:Inglês
出版: Blackwell Science Inc 2004
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在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC1809250/
https://ncbi.nlm.nih.gov/pubmed/15544633
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1365-2249.2004.02633.x
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