Identification of Novel Roles of the Cytochrome P450 System in Early Embryogenesis: Effects on Vasculogenesis and Retinoic Acid Homeostasis

The cytochrome P450-dependent monooxygenase system catalyzes the metabolism of xenobiotics and endogenous compounds, including hormones and retinoic acid. In order to establish the role of these enzymes in embryogenesis, we have inactivated the system through the deletion of the gene for the electro...

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Autori principali: Otto, Diana M. E., Henderson, Colin J., Carrie, Dianne, Davey, Megan, Gundersen, Thomas E., Blomhoff, Rune, Adams, Ralf H., Tickle, Cheryll, Wolf, C. Roland
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Society for Microbiology 2003
Soggetti:
Cell Growth and Development
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC180925/
https://ncbi.nlm.nih.gov/pubmed/12917333
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.23.17.6103-6116.2003
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