Identification of Novel Roles of the Cytochrome P450 System in Early Embryogenesis: Effects on Vasculogenesis and Retinoic Acid Homeostasis

The cytochrome P450-dependent monooxygenase system catalyzes the metabolism of xenobiotics and endogenous compounds, including hormones and retinoic acid. In order to establish the role of these enzymes in embryogenesis, we have inactivated the system through the deletion of the gene for the electro...

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Autores principales: Otto, Diana M. E., Henderson, Colin J., Carrie, Dianne, Davey, Megan, Gundersen, Thomas E., Blomhoff, Rune, Adams, Ralf H., Tickle, Cheryll, Wolf, C. Roland
Formato: Artigo
Lenguaje:Inglês
Publicado: American Society for Microbiology 2003
Materias:
Cell Growth and Development
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC180925/
https://ncbi.nlm.nih.gov/pubmed/12917333
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.23.17.6103-6116.2003
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