Neutrophil responses to CRP are not dependent on polymorphism of human FcγRIIA (R131H)

IgG2a mediated in vitro phagocytosis is less effective for individuals homozygous for FcγRIIaR131 allele and such individuals are also more susceptible to certain infections. It has been reported that CRP binds to FcγRIIaR131 but not FcγRIIaH131 and since FcγRIIa is also a major Fc receptor on neutr...

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Autores principales: RODRÍGUEZ, J A, BODMAN-SMITH, K B, RAYNES, J G
Formato: Artigo
Lenguaje:Inglês
Publicado: Blackwell Science Inc 2004
Materias:
Clinical Studies
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC1809209/
https://ncbi.nlm.nih.gov/pubmed/15498037
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1365-2249.2004.02603.x
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