Neutrophil responses to CRP are not dependent on polymorphism of human FcγRIIA (R131H)

IgG2a mediated in vitro phagocytosis is less effective for individuals homozygous for FcγRIIaR131 allele and such individuals are also more susceptible to certain infections. It has been reported that CRP binds to FcγRIIaR131 but not FcγRIIaH131 and since FcγRIIa is also a major Fc receptor on neutr...

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Autori principali: RODRÍGUEZ, J A, BODMAN-SMITH, K B, RAYNES, J G
Natura: Artigo
Lingua:Inglês
Pubblicazione: Blackwell Science Inc 2004
Soggetti:
Clinical Studies
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC1809209/
https://ncbi.nlm.nih.gov/pubmed/15498037
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1365-2249.2004.02603.x
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