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Up-regulation of IL-18 and predominance of a Th1 immune response is a hallmark of lupus nephritis

There is evidence that nephritis is dominated by a Th1 immune response in systemic lupus erythematosus. Since IL-18 promotes polarization of the immune response toward Th1, we investigated the role of this cytokine in lupus nephritis (LN). A total of 133 lupus patients and 44 healthy subjects were e...

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Autores principales: CALVANI, N, RICHARDS, H B, TUCCI, M, PANNARALE, G, SILVESTRIS, F
Formato: Artigo
Lenguaje:Inglês
Publicado: Blackwell Science Inc 2004
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC1809179/
https://ncbi.nlm.nih.gov/pubmed/15373921
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1365-2249.2004.02588.x
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