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Iron down-regulates macrophage anti-tumour activity by blocking nitric oxide production

Although the inhibitory effect of iron on macrophage production of tumoricidal free radical nitric oxide (NO) has been reported, its possible influence on macrophage anti-tumour activity has not been established. In the present study, FeSO(4) markedly reduced IFN-γ + LPS-induced NO synthesis in mous...

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Autori principali: HARHAJI, L, VUCKOVIC, O, MILJKOVIC, D, STOSIC-GRUJICIC, S, TRAJKOVIC, V
Natura: Artigo
Lingua:Inglês
Pubblicazione: Blackwell Science Inc 2004
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC1809097/
https://ncbi.nlm.nih.gov/pubmed/15196250
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1365-2249.2004.02515.x
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