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Mycophenolic acid inhibits activation of inducible nitric oxide synthase in rodent fibroblasts

Mycophenolate mofetil (MMF) is an immunosuppressive drug that acts as a selective inhibitor of inosine monophosphate dehydrogenase (IMPDH). MMF has recently been shown to inhibit the enzymatic activity of inducible NO synthase (iNOS) and subsequent production of the cytotoxic free radical nitric oxi...

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Detalhes bibliográficos
Main Authors: MILJKOVIC, Dj, CVETKOVIC, I, STOSIC-GRUJICIC, S, TRAJKOVIC, V
Formato: Artigo
Idioma:Inglês
Publicado em: Blackwell Science Inc 2003
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1808694/
https://ncbi.nlm.nih.gov/pubmed/12699411
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1046/j.1365-2249.2003.02140.x
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