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Identification of systemically expanded activated T cell clones in MRL/lpr and NZB/W F1 lupus model mice

CD4(+) T lymphocytes play an important role in the pathogenesis of systemic lupus erythematosus (SLE). To characterize the clonal expansion of CD4(+) T cells in murine lupus models, we analysed the T cell clonality in various organs of young and nephritic MRL/lpr and NZB/W F1 mice using reverse tran...

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Autors principals: ZHOU, G, FUJIO, K, SADAKATA, A, OKAMOTO, A, YU, R, YAMAMOTO, K
Format: Artigo
Idioma:Inglês
Publicat: Blackwell Science Inc 2004
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC1809066/
https://ncbi.nlm.nih.gov/pubmed/15147346
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1365-2249.2004.02473.x
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