Induction of hyperthyroidism in mice by intradermal immunization with DNA encoding the thyrotropin receptor

Intramuscular injection with plasmid DNA encoding the human thyrotropin receptor (TSHR) has been known to elicit symptoms of Graves’ disease (GD) in outbred but not inbred mice. In this study, we have examined, firstly, whether intradermal (i.d.) injection of TSHR DNA can induce hyperthyroidism in B...

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Detalhes bibliográficos
Main Authors: BARRETT, K, LIAKATA, E, RAO, P V, WATSON, P F, WEETMAN, A P, LYMBERI, P, BANGA, J P, CARAYANNIOTIS, G
Formato: Artigo
Idioma:Inglês
Publicado em: Blackwell Science Inc 2004
Assuntos:
Animal Studies
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1809053/
https://ncbi.nlm.nih.gov/pubmed/15147342
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1365-2249.2004.02483.x
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