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The role of antigen in the selection of the human V3-23 immunoglobulin heavy chain variable region gene

The immune system mounts antibody responses using few of the available immunoglobulin variable region (IgV) genes with some, such as the V3-23 heavy chain gene, regularly over-represented in responses to many antigens. The reasons for the over-representation of some V genes have not been established...

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Detalhes bibliográficos
Main Authors: MACKWORTH-YOUNG, C G, HARMER, I J, MAGEED, R A
Formato: Artigo
Idioma:Inglês
Publicado em: Blackwell Science Inc 2003
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1808894/
https://ncbi.nlm.nih.gov/pubmed/14632746
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1365-2249.2003.02319.x
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