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Comparative in vitro study of the immunomodulatory activity of humanized and chimeric anti-CD25 monoclonal antibodies

Humanized or chimeric monoclonal antibodies (MoAbs) directed against the interleukin-2 (IL-2) receptor α-chain, CD25, are promising immunosuppressive agents due to improved pharmacokinetic profiles and less toxicity. These MoAbs have been used effectively in preventing and/or treating rejection in s...

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Bibliografiske detaljer
Main Authors: KIRCHER, B, LÄTZER, K, GASTL, G, NACHBAUR, D
Format: Artigo
Sprog:Inglês
Udgivet: Blackwell Science Inc 2003
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC1808889/
https://ncbi.nlm.nih.gov/pubmed/14632747
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1365-2249.2003.02324.x
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