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Identical twins discordant for multiple sclerosis have a shift in their T-cell receptor repertoires
CD4 T-cells have an important role in the autoimmune response in multiple sclerosis (MS). We investigate the possibility that a shift occurs in the T-cell receptor (TR) repertoire of identical twins discordant for MS. We compare the CDR3 spectratype distributions of 24 different TR V beta (TRBV) seg...
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| Main Authors: | , , , , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
Blackwell Science Inc
2003
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1808887/ https://ncbi.nlm.nih.gov/pubmed/14632762 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1365-2249.2003.02327.x |
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