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Bruton's tyrosine kinase defect in dendritic cells from X-linked agammaglobulinaemia patients does not influence their differentiation, maturation and antigen-presenting cell function
X-linked agammaglobulinaemia (XLA) is a primary immunodeficiency disease characterized by very low levels or even absence of circulating antibodies. The immunological defect is caused by deletions or mutations of Bruton's tyrosine kinase gene (Btk), whose product is critically involved in the m...
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Asıl Yazarlar: | , , , , , , , |
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Materyal Türü: | Artigo |
Dil: | Inglês |
Baskı/Yayın Bilgisi: |
Blackwell Publishing Inc
2003
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Konular: | |
Online Erişim: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1808743/ https://ncbi.nlm.nih.gov/pubmed/12823285 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1046/j.1365-2249.2003.t01-1-02178.x |
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