Bruton's tyrosine kinase defect in dendritic cells from X-linked agammaglobulinaemia patients does not influence their differentiation, maturation and antigen-presenting cell function

X-linked agammaglobulinaemia (XLA) is a primary immunodeficiency disease characterized by very low levels or even absence of circulating antibodies. The immunological defect is caused by deletions or mutations of Bruton's tyrosine kinase gene (Btk), whose product is critically involved in the m...

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Detalhes bibliográficos
Main Authors: GAGLIARDI, M C, FINOCCHI, A, ORLANDI, P, CURSI, L, CANCRINI, C, MOSCHESE, V, MIYAWAKI, T, ROSSI, P
Formato: Artigo
Idioma:Inglês
Publicado em: Blackwell Publishing Inc 2003
Assuntos:
Clinical Studies
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1808743/
https://ncbi.nlm.nih.gov/pubmed/12823285
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1046/j.1365-2249.2003.t01-1-02178.x
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